Creatine phosphokinase in mammalian brain

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Creatine phosphokinase in mammalian brain.

Hawk, P. B., Oser, B. L. & Summerson, W. H. (1947). Practical Phy8iotogical Chemi8try. London: Churchill. Heilbrunn, L. V. (1947). An Outline of General Phy8iology. Philadelphia: Saunders. Hoagland, H. & Stone, D. (1948). Amer. J. Phy8iol. 152, 423. Klein, J. R. & Olsen, N. S. (1947). J. biol. Chem. 167, 747. Krebs, H. A. (1950). Biochim. biophy8. Acta, Am8t., 4, 249. Krebs, H. A. & Eggleston, ...

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Plasma creatine phosphokinase (GPK) was estimated from unmedicated schizophrenics to evaluate its significance in the diagnosis. The mean value of CPK in schizophrenics is 78.41±5.78 IU/L (n=49) as against control value of 27.45±2.27 IU/L (n = 36). The statistical analysis showed significance (p<0.05). The study finds its importance in view of the earlier reports suggesting the diagnostic value...

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Cardiac Specific Creatine Phosphokinase

The specificity and sensitivity of serum creatine phosphokinase cardiac specific isoenzyme (MB) in the diagnosis of acute myocardial infarction (AM I) was evaluated. An ion-exchange chromatographic technique was used to isolate MB. Sera layered on mini-columns of DEAE-Sephadex were eluted with Tris-buffered sodium chloride. Quantification of isolated MB was performed by creatine phosphokinase (...

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Serum creatine phosphokinase activity in acute psychosis.

During the last 7 years, there have been a number of investigations of the incidence of various types of neuromuscular dysfunction in patients with schizophrenic and affective illnesses and their first-degree relatives in comparison with appropriate controls, including nonpsychotic psychiatric patients. Before reviewing these studies, it may be of value to discuss why neuromuscular dysfunction ...

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Creatine phosphokinase activity in rabbit alveolar macrophages.

An enzyme is present in extracts of rabbit alveolar macrophage which can catalyze the reaction of creatine phosphate with adenosine diphosphate to form adenosine triphosphate and creatine. The enzyme is moderately activated by reduced glutathione, has a pH optimum between pH 6.5 and 7.0, and shows an absolute requirement for Mg(2+). The K(m) for creatine phosphate is approximately 3.6 mm while ...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1952

ISSN: 0306-3283

DOI: 10.1042/bj0520295